Alopecia, ascites, and incomplete regeneration after 85 to 90 per cent liver resection

Alopecia, ascites, and incomplete regeneration after 85 to 90 per cent liver resection.

A nineteen year old female underwent 85 to 90 per cent partial hepatectomy to treat a minimal deviation hepatoma. Observations afterwards suggested that the limit of resection compatible with survival had been reached. She recovered perfect health after many months, although liver regeneration was not complete. Severe but eventually reversible alopecia and ascites developed postoperatively, und...

Increased liver regeneration rate and decreased liver function after synchronous liver and colon resection in rats

BACKGROUND The surgical strategy for the treatment of colorectal cancer and synchronous liver metastases remains controversial. The aim of the present study was to investigate the effects of colonic resection on liver function and regeneration in a rat model. METHODS Ninety-six Sprague-Dawley rats were block-randomized into six groups: Group I had a laparotomy performed. Group II had 1 cm col...

Cellular Liver Regeneration after Extended Hepatic Resection in Pigs

BACKGROUND The liver has an enormous capacity to regenerate itself. The aim of this study was to evaluate whether the regeneration is due to hypertrophy or hyperplasia of the remnant liver after extended resection and whether a portosystemic shunt is beneficial. MATERIAL AND METHODS An extended left hemihepatectomy was performed in 25 pigs, and in 14 after performing a portosystemic shunt. Du...

Hyperplasia vs hypertrophy in tissue regeneration after extensive liver resection

AIM To address to what extent hypertrophy and hyperplasia contribute to liver mass restoration after major tissue loss. METHODS The ability of the liver to regenerate is remarkable on both clinical and biological grounds. Basic mechanisms underlying this process have been intensively investigated. However, it is still debated to what extent hypertrophy and hyperplasia contribute to liver mass...

Liver Regeneration in Rats after Liver Resection and Small-for-size Liver Transplantation from Living Donors